Welcome to the Deep Brain Dynamics laboratory homepage,

Here you will find information about the research activities of me and my group. We are part of the Dpt of Clinical Neurosciences at the University Hospital in Lausanne (CHUV) and a member of the clinical division of the Defitech Centre for Interventional Neurotherapies (.NeuroRestore) at the Ecole Polytechnique Fédérale de Lausanne (EPFL).

Our focus is on the development of neuromodulation therapies of brain and spinal-cord to alleviate impairments of gait and balance in patients with Parkinson's disease. We combine a comprehensive set of neurotechnologies for monitoring and interacting with whole-body kinematics, kinetics, and forces, in parallel to cortical and subcortical brain signals, as a way to link brain and motor states during a wide range of locomotor activities of daily living.

Our goal is to design and push forward therapies that can intelligently interact with ongoing pathological neural dynamics : Robust, clinically-relevant treatments must ecologically exploit (rather than over-write) the capabilities of the underlying neural circuits. They are thus critically contingent on a mechanistic understanding of the neural processes that underlie motor function and dysfunction.



Check out our latest publication on the development of a new spinal cord stimulation therapy to alleviate deficits of gait and balance in Parkinson's disease !


We thank the Fondation Parkinson Move for a wonderful evening at their 2023 'Soirée de Soutien', and for their continuous support of our activities. We will see each other in October 8 for the next challenge !


Check out our latest publication on the decoding of locomotor functions in patients with PD.
Using a last generation deep brain stimulation implant able to simultaneously stimulate and record the brain, we identified the neural activity patterns that correlate with normal and pathological gait. We then developed machine learning algorithms able to predict in real-time different aspects of walking.


We had the opportunity to show our activities and advances in the medical documentary "36.9" on Swiss National TV: "Comment j'ai géré mon Parkinson disease et révé d'une thérapie qui fonctionne" .


Eduardo Martin Moraud 2023. 3D designs and photography by Jimmy Ravier. All rights reserved